Dale Zimmerman

Department of Statistics and Actuarial Science,

University of Iowa


STRUCTURED ANTEDEPENDENCE MODELS FOR LONGITUDINAL DATA

Antedependence (AD) models are a useful, though not widely known, class of models for the covariance structure of longitudinal data. Like stationary autoregressive models, AD models allow for serial correlation within subjects, but they are more general in the sense that they do not stipulate that the variance is constant over time nor that correlations between measurements equidistant in time are equal. Thus, AD models provide a more parsimonious approach to the analysis of nonstationary data than the completely unstructured classical multivariate approach.

For some nonstationary longitudinal data, however, a highly structured AD model may be more useful than an unstructured AD model. For example, if the variances increase over time, as is common in growth studies, or if measurements equidistant in time become more highly correlated as the study progresses, then a model that incorporates these structural forms of nonstationarity is likely to be more useful. In this talk I review AD models in general and then I introduce some structured AD models. Properties of the models and estimation of model parameters by maximum likelihood are considered. An example, replete with an analysis using PROC MIXED, illustrates the usefulness of the models.


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